Poor MCC (mucociliary clearance) of the upper respiratory tract leads to mucus pooling within the middle ear cleft, nose and paranasal sinuses. This results in a high incidence of otitis media with effusion (46–86% of patients), hearing loss (25–36%) and nasal discharge or blockage (76–88%). Where one would normally expect resolution of glue ear and nasal discharge in an otherwise healthy child by 8years, symptoms in PCD children persist longer and not infrequently into adulthood.

https://adc.bmj.com/content/99/9/850 

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“Kartageners Syndrome”, “Immotile Ciliary Syndrome”, or “Dismotile Ciliary Syndrome” have been outdated terms since the early 1980s for primary ciliary dyskinesia due to the advancement of the scientific understanding of cilia.

https://pcdfoundation.org/pcd-terminology/

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This preliminary data suggests that structural lung disease in PCD has unique features both in lobar localisation and structural nature and that the use of CF derived scoring systems which do not take these features into consideration may potentially result in incomplete assessment of the bronchiectasis associated with PCD. In order to accurately describe the range of structural changes seen on CT scans in PCD, and indeed the evolution of these changes over time, a scoring system based solely on findings from PCD CT scans should be developed using the same multicentre, international, large scale strategy used to develop the CF CT scores.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101071/

The more you know…

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We have several ways that you can donate to PCD Smiles;

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Thank you for your consideration!